Jan 12, 2021
Windows 8 Lite Remix Edition released
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Category:Ubuntu derivativesA major challenge for the animal industry is to identify and incorporate transgenic traits into a genetic background that is viable and resilient for commercial use. Researchers have investigated different traits such as increased milk production, which has been achieved by overexpressing beta-lactoglobulin. However, these types of proteins are a component of the mucin superfamily and often affect the viability of the mammary gland and other tissues. See E. Ledent et al., Arch. Biochem. Biophys. (1999), 367, 158-165. Some milk protein genes have also been implicated in important disease resistance phenotypes, such as disease resistance to mastitis and udder infection. See, U.S. Pat. No. 6,673,760; S. W. Kaul, Curr. Opin. Bio. (2003), 14, 287-297; J. Goodall, FEMS Microbiol. Lett. (2004), 259, 35-42; Y. L. Lin et al., J. Bacteriol. (2005), 187, 7861-7871.
In order to ensure the viability of a transgenic animal, transgenic animals with certain defined genetic backgrounds must be selectively propagated and preferably rederived from one or more founders with a predictable phenotype that can be identified in each animal. In contrast, traditional breeding schemes that focus on non-genetic factors such as coat color are generally too slow and impractical.
Applicants have recognized that it would be desirable to develop a method that could selectively propagate transgenic animals having a desired phenotype that can be detected by simple phenotypic means, such as by examining milk protein content. Applicants have also recognized that it would be desirable to develop a method of selectively propagating transgenic animals having a desired phenotype that can be identified by simple phenotypic means. Further, it would be desirable to develop a method that is rapid and efficient and would minimize loss of viable founder stock. Applicants have now invented such methods and compositions.// Targeted by JavaCPP version 1.5.4: DO NOT EDIT THIS FILE
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